EN460

Biorbyt

EN460

10

496807-64-8

Research Use Only

C22H12CLF3N2O4

460.7898951

EN460 is a specific mall molecule inhibitor of endoplasmic reticulum oxidation 1 (ERO1), interacts selectively with the reduced, active form of ERO1alpha and prevents its reoxidation (IC50=1.9 uM).

FC(F)(F)C1=NN(C2=CC(C(O)=O)=C(Cl)C=C2)C(/C1=C\C3=CC=C(C4=CC=CC=C4)O3)=O

12352200