Endoxifen (Z-isomer)

MedChem Express

Endoxifen (Z-isomer) [112093-28-4]

10

112093-28-4

Research Use Only

99.20

C25H27NO2

373.49

Endoxifen Z-isomer is an oral active Tamoxifen (HY-13757A) metabolite, inducing an anti-estrogenic effect in breast cancer cells expressing ERalpha. Endoxifen Z-isomer inhibits hERG. This effect is concentration-dependent, with an IC 50 value of 1.6 microM [1] [2] [3] [4] .

OC1=CC=C(/C(C2=CC=C(OCCNC)C=C2)=C(C3=CC=CC=C3)\CC)C=C1

-20°C,2°C to 8°C

12352200