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ENY2 antibody [GT245]

Research Use Only
GTX629542
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetENY2
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    ENY2 antibody [GT245]
  • Delivery Days Customer
    9
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    GT245
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID56943
  • Target name
    ENY2
  • Target description
    ENY2 transcription and export complex 2 subunit
  • Target synonyms
    DC6; e(y)2; enhancer of yellow 2 homolog; enhancer of yellow 2 transcription factor homolog; Sus1; transcription and mRNA export factor ENY2
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. May also participate in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
  • Reactivity
    Human, Rat
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • Systematic Functional Annotation of Somatic Mutations in Cancer. Ng PK et al., 2018 Mar 12, Cancer Cell
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