ENY2 antibody [GT245]
![Research Use Only](static/images/certificates/ruo.jpg)
GTX629542
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetENY2
Overview
- SupplierGeneTex
- Product NameENY2 antibody [GT245]
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT245
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID56943
- Target nameENY2
- Target descriptionENY2 transcription and export complex 2 subunit
- Target synonymsDC6; e(y)2; enhancer of yellow 2 homolog; enhancer of yellow 2 transcription factor homolog; Sus1; transcription and mRNA export factor ENY2
- HostMouse
- IsotypeIgG1
- Scientific DescriptionComponent of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. May also participate in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
- ReactivityHuman, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Systematic Functional Annotation of Somatic Mutations in Cancer. Ng PK et al., 2018 Mar 12, Cancer CellRead more