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ENY2 antibody

Name: ENY2 antibody
SKU: GTX128034_G10
Availability: BackOrder

GTX128034

ApplicationsImmunoPrecipitation, Western Blot

Product group Antibodies

TargetENY2

Overview

Supplier
GeneTex
Product Name
ENY2 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoPrecipitation, Western Blot
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.62 mg/ml
Conjugate
Unconjugated
Gene ID56943
Target name
ENY2
Target description
ENY2 transcription and export complex 2 subunit
Target synonyms
DC6, Sus1, e(y)2, transcription and mRNA export factor ENY2, enhancer of yellow 2 homolog, enhancer of yellow 2 transcription factor homolog
Host
Rabbit
Isotype
IgG
Protein IDQ9NPA8
Protein Name
Transcription and mRNA export factor ENY2
Scientific Description
Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. May also participate in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Li W, Atanassov BS, Lan X, et al. Cytoplasmic ATXN7L3B Interferes with Nuclear Functions of the SAGA Deubiquitinase Module. Mol Cell Biol. 2016,36(22):2855-2866. doi: 10.1128/MCB.00193-16
Read this paper