ENY2 antibody
GTX128034
ApplicationsImmunoPrecipitation, Western Blot
Product group Antibodies
ReactivityHuman
TargetENY2
Overview
- SupplierGeneTex
- Product NameENY2 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.62 mg/ml
- ConjugateUnconjugated
- Gene ID56943
- Target nameENY2
- Target descriptionENY2 transcription and export complex 2 subunit
- Target synonymsDC6; e(y)2; enhancer of yellow 2 homolog; enhancer of yellow 2 transcription factor homolog; Sus1; transcription and mRNA export factor ENY2
- HostRabbit
- IsotypeIgG
- Protein IDQ9NPA8
- Protein NameTranscription and mRNA export factor ENY2
- Scientific DescriptionComponent of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. May also participate in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Cytoplasmic ATXN7L3B Interferes with Nuclear Functions of the SAGA Deubiquitinase Module. Li W et al., 2016 Nov 15, Mol Cell BiolRead more