EphB2 antibody [2D12C6]

GeneTex

EphB2 antibody [2D12C6]

9

WB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry

Research Use Only

Monoclonal

2D12C6

Unconjugated

EPHB2

EPH receptor B2

BDPLT22; CAPB; developmentally-regulated Eph-related tyrosine kinase; DRT; EK5; elk-related tyrosine kinase; eph tyrosine kinase 3; EPH-like kinase 5; ephrin type-B receptor 2; EPHT3; ERK; Hek5; PCBC; protein-tyrosine kinase HEK5; renal carcinoma antigen NY-REN-47; Tyro5; tyrosine-protein kinase receptor EPH-3; tyrosine-protein kinase TYRO5

Mouse

IgG2b

Ephrin type-B receptor 2

This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]

Human

-20°C or -80°C,2°C to 8°C

12352203