The cell proliferation of the TF-1 human erythroleukemic cell line induced by Human Erythropoietin/EPO and neutralization by Erythropoietin Antibody. Proliferation elicited by Recombinant Human Erythropoietin/EPO (0.4 ng/mL) is neutralized by increasing concentrations of EPO antibody [HL2752] (GTX639615).
![Indirect ELISA analysis was performed by coating the plate with recombinant HEK293 expressed, full-length EPO protein, His tag (50 ng). Coated protein was probed with EPO antibody [HL2752] (GTX639615) (40960-4.88*10 -3 nM). Goat anti-rabbit IgG antibody (HRP) (GTX213110-01) (1:10000) was used to detect the bound primary antibody. EC50 : 36.04 nM](https://www.genetex.com/upload/website/prouct_img/normal/GTX639615/GTX639615_45467_20251121_ELISA_Indirect_EC50_25112800_357.webp "Indirect ELISA analysis was performed by coating the plate with recombinant HEK293 expressed, full-length EPO protein, His tag (50 ng). Coated protein was probed with EPO antibody [HL2752] (GTX639615) (40960-4.88*10 -3 nM). Goat anti-rabbit IgG antibody (HRP) (GTX213110-01) (1:10000) was used to detect the bound primary antibody. EC50 : 36.04 nM")
The cell proliferation of the TF-1 human erythroleukemic cell line induced by Human Erythropoietin/EPO and neutralization by Erythropoietin Antibody. Proliferation elicited by Recombinant Human Erythropoietin/EPO (0.4 ng/mL) is neutralized by increasing concentrations of EPO antibody [HL2752] (GTX639615).
EPO antibody [HL2752]
GTX639615
ApplicationsNeutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetEPO
Overview
- SupplierGeneTex
- Product NameEPO antibody [HL2752]
- Delivery Days Customer7
- ApplicationsNeutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHL2752
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2056
- Target nameEPO
- Target descriptionerythropoietin
- Target synonymsDBAL, ECYT5, EP, MVCD2, erythropoietin, epoetin
- HostRabbit
- IsotypeIgG
- Protein IDP01588
- Protein NameErythropoietin
- Scientific DescriptionThis gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies. [provided by RefSeq, Aug 2017]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
Datasheet
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