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Epoxomicin [134381-21-8]

Research Use Only
HY-13821
MedChem Express
CAS Number134381-21-8
Product group Chemicals
Estimated Purity95%
Molecular Weight554.72
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Epoxomicin [134381-21-8]
  • Delivery Days Customer
    10
  • CAS Number
    134381-21-8
  • Certification
    Research Use Only
  • Estimated Purity
    95%
  • Molecular Formula
    C28H50N4O7
  • Molecular Weight
    554.72
  • Scientific Description
    Epoxomicin (BU-4061T) is an epoxyketone-containing natural product and a potent, selective and irreversible proteasome inhibitor. Epoxomicin covalently binds to the LMP7, X, MECL1, and Z catalytic subunits of the proteasome and potently inhibits primarily the chymotrypsin-like activity. Epoxomicin can cross the blood-brain barrier. Epoxomicin has strongly antitumor and anti-inflammatory activity.
  • SMILES
    O=C([C@@H](NC([C@H]([C@@H](C)O)NC([C@@H](NC([C@H]([C@@H](C)CC)N(C)C(C)=O)=O)[C@@H](C)CC)=O)=O)CC(C)C)[C@@]1(C)CO1
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200