Epoxomicin
M2193
CAS Number134381-21-8
Product group Chemicals
Estimated Purity0.9857
Molecular Weight554.72
Overview
- SupplierAbMole BioScience
- Product NameEpoxomicin
- Delivery Days Customer9
- CAS Number134381-21-8
- Category SupplierChemical
- CertificationResearch Use Only
- Estimated Purity0.9857
- Molecular FormulaC28H50N4O7
- Molecular Weight554.72
- Scientific DescriptionEpoxomicin (BU-4061T) is a cell-permeable, selective and irreversible proteasome inhibitor with an IC50 value of 4 nM. Epoxomicin covalently binds to the LMP7, X, MECL1, and Z catalytic subunits of the proteasome and potently inhibits primarily the chymotrypsin-like activity. Epoxomicin can cross the blood-brain barrier.
- SMILESCCC(C)C(NC(=O)C(C(C)CC)N(C)C(C)=O)C(=O)NC(=O)C(NC(CC(C)C)C(=O)C1(C)CO1)C(C)O
- UNSPSC12352200