Western blot analysis of extracts of various cell lines using Estrogen Receptor alpha Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using Estrogen Receptor alpha Polyclonal Antibody at dilution of 1:1000.
ER alpha Polyclonal Antibody
E-AB-60073
Product group Antibodies
Overview
- SupplierElabscience
- Product NameER alpha Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.
- UNSPSC12352203