ICC/IF analysis of COS7 cells transiently transfected with ERAB plasmid using GTX84346 ERAB antibody [10B4].
![IHC-P analysis of colon adenocarcinoma tissue using GTX84346 ERAB antibody [10B4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84346/GTX84346_2637_IHC-P_w_23061420_734.webp "IHC-P analysis of colon adenocarcinoma tissue using GTX84346 ERAB antibody [10B4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50")
![IHC-P analysis of liver carcinoma tissue using GTX84346 ERAB antibody [10B4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84346/GTX84346_2638_IHC-P_w_23061420_201.webp "IHC-P analysis of liver carcinoma tissue using GTX84346 ERAB antibody [10B4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50")
![IHC-P analysis of kidney tissue using GTX84346 ERAB antibody [10B4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84346/GTX84346_2639_IHC-P_w_23061420_159.webp "IHC-P analysis of kidney tissue using GTX84346 ERAB antibody [10B4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50")
![IHC-P analysis of liver tissue using GTX84346 ERAB antibody [10B4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84346/GTX84346_2640_IHC-P_w_23061420_238.webp "IHC-P analysis of liver tissue using GTX84346 ERAB antibody [10B4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50")
![IHC-P analysis of pancreas tissue using GTX84346 ERAB antibody [10B4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84346/GTX84346_2641_IHC-P_w_23061420_530.webp "IHC-P analysis of pancreas tissue using GTX84346 ERAB antibody [10B4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50")
![FACS analysis of HeLa cells using GTX84346 ERAB antibody [10B4]. Red : Primary antibody Blue : Negative control antibody](https://www.genetex.com/upload/website/prouct_img/normal/GTX84346/GTX84346_371_FACS_w_23061420_499.webp "FACS analysis of HeLa cells using GTX84346 ERAB antibody [10B4]. Red : Primary antibody Blue : Negative control antibody")
![FACS analysis of Jurkat cells using GTX84346 ERAB antibody [10B4]. Red : Primary antibody Blue : Negative control antibody](https://www.genetex.com/upload/website/prouct_img/normal/GTX84346/GTX84346_372_FACS_w_23061420_720.webp "FACS analysis of Jurkat cells using GTX84346 ERAB antibody [10B4]. Red : Primary antibody Blue : Negative control antibody")
![WB analysis of HEK293T cells transfected with ERAB plasmid (Right) or empty vector (Left) for 48 hrs using GTX84346 ERAB antibody [10B4]. Loading : 5 ug per lane](https://www.genetex.com/upload/website/prouct_img/normal/GTX84346/GTX84346_4297_WB_w_23061420_268.webp "WB analysis of HEK293T cells transfected with ERAB plasmid (Right) or empty vector (Left) for 48 hrs using GTX84346 ERAB antibody [10B4]. Loading : 5 ug per lane")
![WB analysis of various cell lines using GTX84346 ERAB antibody [10B4]. Loading : 35 ug per lane](https://www.genetex.com/upload/website/prouct_img/normal/GTX84346/GTX84346_4298_WB_w_23061420_802.webp "WB analysis of various cell lines using GTX84346 ERAB antibody [10B4]. Loading : 35 ug per lane")
ICC/IF analysis of COS7 cells transiently transfected with ERAB plasmid using GTX84346 ERAB antibody [10B4].
ERAB antibody [10B4]
GTX84346
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetHSD17B10
Overview
- SupplierGeneTex
- Product NameERAB antibody [10B4] - Overexpression Validated
- Delivery Days Customer9
- Application Supplier NoteWB: 1:2000. ICC/IF: 1:100. IHC-P: 1:50. FACS: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID10B4
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3028
- Target nameHSD17B10
- Target descriptionhydroxysteroid 17-beta dehydrogenase 10
- Target synonyms17b-HSD10; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type-2; ABAD; AB-binding alcohol dehydrogenase; amyloid-beta peptide binding alcohol dehydrogenase; CAMR; DUPXp11.22; endoplasmic reticulum-associated amyloid beta-peptide-binding protein; ERAB; HADH2; HCD2; HSD10MD; MHBD; mitochondrial ribonuclease P protein 2; mitochondrial RNase P subunit 2; MRPP2; MRX17; MRX31; MRXS10; SCHAD; SDR5C1; short chain L-3-hydroxyacyl-CoA dehydrogenase type 2; short chain type dehydrogenase/reductase XH98G2
- HostMouse
- IsotypeIgG1
- Protein IDQ99714
- Protein Name3-hydroxyacyl-CoA dehydrogenase type-2
- Scientific DescriptionFunctions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203