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ERK1 (phospho Thr202/Tyr204) + ERK2 (phospho Thr185/Tyr187) antibody [HL173]

GTX635617
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityDrosophila, Human, Mouse, Rat
TargetMAPK3
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Overview

  • Supplier
    GeneTex
  • Product Name
    ERK1 (phospho Thr202/Tyr204) + ERK2 (phospho Thr185/Tyr187) antibody [HL173]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody detects Erk1 and Erk2 when dually phosphorylated at Thr202 and Tyr204 of Erk1 (Thr185 and Tyr187 of Erk2), and singly phosphorylated at Tyr204.
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    HL173
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5595
  • Target name
    MAPK3
  • Target description
    mitogen-activated protein kinase 3
  • Target synonyms
    ERK1; ERK-1; ERT2; extracellular signal-regulated kinase 1; extracellular signal-related kinase 1; HS44KDAP; HUMKER1A; insulin-stimulated MAP2 kinase; MAPK 1; microtubule-associated protein 2 kinase; mitogen-activated protein kinase 3; P44ERK1; p44-ERK1; P44MAPK; p44-MAPK; PRKM3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP27361
  • Protein Name
    Mitogen-activated protein kinase 3
  • Scientific Description
    The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]
  • Reactivity
    Drosophila, Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • GIF-2209, an Oxindole Derivative, Accelerates Melanogenesis and Melanosome Secretion via the Modification of Lysosomes in B16F10 Mouse Melanoma Cells. Watanabe M et al., 2021 Dec 28, Molecules
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  • FTY720 in resistant human epidermal growth factor receptor 2-positive breast cancer. Chung WP et al., 2022 Jan 7, Sci Rep
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  • Angiotensin-(1-7) treatment blocks lipopolysaccharide-induced organ damage, platelet dysfunction, and IL-6 and nitric oxide production in rats. Tsai HJ et al., 2021 Jan 12, Sci Rep
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  • PM2.5 facilitates IL-6 production in human osteoarthritis synovial fibroblasts via ASK1 activation. Liu JF et al., 2021 Mar, J Cell Physiol
    Read more