ERRalpha antagonist-1 [1072145-33-5]

TargetMol Chemicals

ERRalfa antagonist-1

10

1072145-33-5

Chemical

Research Use Only

ERRalfa antagonist-1

C21H19N3S2

377.53

ERRalpha antagonist-1 (ERR+/- antagonist-1) is a high-affinity, selective antagonist of the estrogen-related receptor alpha (ERRalpha). It effectively prevents the interaction of ERRalpha with both Proliferator-activated Receptor gamma Coactivator-1alpha (PGC-1alpha) and PGC-1beta, displaying IC50 values of 170 nM and 180 nM, respectively. Notably, ERRalpha antagonist-1 does not interfere with the interactions involving ERRbeta or ERRgamma and the PGC-1alpha and PGC-1beta coactivators. Furthermore, it does not affect the interaction between either ERalpha or ERbeta and PGC-1alpha or SRC-1.

3 years

C1CN=C(S1)N1CCS\C1=N/C1c2ccccc2C=Cc2ccccc12

-20°C

12352200