EVI1 antibody, Internal
GTX88191
Overview
- SupplierGeneTex
- Product NameEVI1 antibody, Internal
- Delivery Days Customer7
- Antibody SpecificityThis antibody is expected to recognize all reported isoforms (NP_001098547.3; NP_005232.2; NP_004982.2; NP_001157471.1; NP_001157472.1). Reported variants represent identical protein: NP_001098548.2, NP_005232.2
- Application Supplier NoteWB: 1-3microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID2122
- Target nameMECOM
- Target descriptionMDS1 and EVI1 complex locus
- Target synonymsAML1-EVI-1; AML1-EVI-1 fusion protein; ecotropic virus integration site 1 protein homolog; EVI1; histone-lysine N-methyltransferase MECOM; KMT8E; MDS1; MDS1 and EVI1 complex locus protein EVI1; MDS1 and EVI1 complex locus protein MDS1; MDS1-EVI1; myelodysplasia syndrome-associated protein 1; oncogene EVI1; PR domain 3; PRDM3; RUSAT2; zinc finger protein Evi1
- HostGoat
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203