EWSR1 antibody detects EWSR1 protein at nucleus on mouse testis by immunohistochemical analysis. Sample: Paraffin-embedded mouse testis. EWSR1 antibody (GTX114069) dilution: 1:500.
Antigen Retrieval: Trilogy? (EDTA based, pH 8.0) buffer, 15min
EWSR1 antibody detects EWSR1 protein at nucleus on mouse testis by immunohistochemical analysis. Sample: Paraffin-embedded mouse testis. EWSR1 antibody (GTX114069) dilution: 1:500.
Antigen Retrieval: Trilogy? (EDTA based, pH 8.0) buffer, 15min
EWSR1 antibody
GTX114069
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetEWSR1
Overview
- SupplierGeneTex
- Product NameEWSR1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.18 mg/ml
- ConjugateUnconjugated
- Gene ID2130
- Target nameEWSR1
- Target descriptionEWS RNA binding protein 1
- Target synonymsEWS, EWS-FLI1, RNA-binding protein EWS, Ewing sarcoma breakpoint region 1, Ewings sarcoma EWS-Fli1 (type 1) oncogene
- HostRabbit
- IsotypeIgG
- Protein IDQ01844
- Protein NameRNA-binding protein EWS
- Scientific DescriptionThis gene encodes a putative RNA binding protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in two products. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Menon S, Breese MR, Lin YP, et al. FET fusion oncoproteins disrupt physiologic DNA repair networks and induce ATR synthetic lethality in cancer. Res Sq. 2023,:pii: rs.3.rs-2869150. doi: 10.21203/rs.3.rs-2869150/v1.Read this paper
- Menon S, Gracilla D, Breese MR, et al. FET fusion oncoproteins disrupt physiologic DNA repair and create a targetable opportunity for ATR inhibitor therapy. bioRxiv. 2025,:pii: 2023.04.30.538578. doi: 10.1101/2023.04.30.538578.Read this paper
- Kong X, Cruz GMS, Trinh SL, et al. Biphasic recruitment of TRF2 to DNA damage sites promotes non-sister chromatid homologous recombination repair. J Cell Sci. 2018,131(23). doi: 10.1242/jcs.219311Read this paper
- Sundararaman B, Zhan L, Blue SM, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016,61(6):903-13. doi: 10.1016/j.molcel.2016.02.012Read this paper
Datasheet
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