EWSR1 antibody

Name: EWSR1 antibody
SKU: GTX114069_G10
Availability: BackOrder

GTX114069

ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetEWSR1

Overview

Supplier
GeneTex
Product Name
EWSR1 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.18 mg/ml
Conjugate
Unconjugated
Gene ID2130
Target name
EWSR1
Target description
EWS RNA binding protein 1
Target synonyms
EWS, EWS-FLI1, RNA-binding protein EWS, Ewing sarcoma breakpoint region 1, Ewings sarcoma EWS-Fli1 (type 1) oncogene
Host
Rabbit
Isotype
IgG
Protein IDQ01844
Protein Name
RNA-binding protein EWS
Scientific Description
This gene encodes a putative RNA binding protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in two products. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Menon S, Breese MR, Lin YP, et al. FET fusion oncoproteins disrupt physiologic DNA repair networks and induce ATR synthetic lethality in cancer. Res Sq. 2023,:pii: rs.3.rs-2869150. doi: 10.21203/rs.3.rs-2869150/v1.
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Menon S, Gracilla D, Breese MR, et al. FET fusion oncoproteins disrupt physiologic DNA repair and create a targetable opportunity for ATR inhibitor therapy. bioRxiv. 2025,:pii: 2023.04.30.538578. doi: 10.1101/2023.04.30.538578.
Read this paper
Kong X, Cruz GMS, Trinh SL, et al. Biphasic recruitment of TRF2 to DNA damage sites promotes non-sister chromatid homologous recombination repair. J Cell Sci. 2018,131(23). doi: 10.1242/jcs.219311
Read this paper
Sundararaman B, Zhan L, Blue SM, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016,61(6):903-13. doi: 10.1016/j.molcel.2016.02.012
Read this paper