Exonuclease 1 antibody
GTX109891
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetEXO1
Overview
- SupplierGeneTex
- Product NameExonuclease 1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration2 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID9156
- Target nameEXO1
- Target descriptionexonuclease 1
- Target synonymsexonuclease 1; HEX1; hExoI; rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1
- HostRabbit
- IsotypeIgG
- Protein IDQ9UQ84
- Protein NameExonuclease 1
- Scientific DescriptionThis gene encodes a protein with 5 to 3 exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Increased Resection at DSBs in G(2)-Phase Is a Unique Phenotype Associated with DNA-PKcs Defects That Is Not Shared by Other Factors of c-NHEJ. Xiao H et al., 2022 Jul 2, CellsRead more
- WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity. Elb®k CR et al., 2022 Jan 18, Cell RepRead more
- Sex-specific differences in DNA double-strand break repair of cycling human lymphocytes during aging. Rall-Scharpf M et al., 2021 Sep 10, Aging (Albany NY)Read more
- PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells. Kim JJ et al., 2020 Oct 15, Mol CellRead more
- Vpu modulates DNA repair to suppress innate sensing and hyper-integration of HIV-1. Volcic M et al., 2020 Oct, Nat MicrobiolRead more
- E2F1 proteolysis via SCF-cyclin F underlies synthetic lethality between cyclin F loss and Chk1 inhibition. Burdova K et al., 2019 Oct 15, EMBO JRead more
- SMYD3 Promotes Homologous Recombination via Regulation of H3K4-mediated Gene Expression. Chen YJ et al., 2017 Jun 19, Sci RepRead more
- DNA damage tolerance pathway involving DNA polymerase iota and the tumor suppressor p53 regulates DNA replication fork progression. Hampp S et al., 2016 Jul 26, Proc Natl Acad Sci U S ARead more
- Quantitation of DNA double-strand break resection intermediates in human cells. Zhou Y et al., 2014 Feb, Nucleic Acids ResRead more
- DNA-dependent protein kinase regulates DNA end resection in concert with Mre11-Rad50-Nbs1 (MRN) and ataxia telangiectasia-mutated (ATM). Zhou Y et al., 2013 Dec 27, J Biol ChemRead more