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WB analysis of various samples using GTX82503 EZH2 antibody. Lane 1: HeLa whole cell lysate Lane 2: Jurkat whole cell lysate Lane 3: MCF-7 whole cell lysate Lane 4: Neuro-2a whole cell lysate Lane 5: T47D whole cell lysate Loading : 20 microg per lane Dilution : 1:2000
WB analysis of various samples using GTX82503 EZH2 antibody. Lane 1: HeLa whole cell lysate Lane 2: Jurkat whole cell lysate Lane 3: MCF-7 whole cell lysate Lane 4: Neuro-2a whole cell lysate Lane 5: T47D whole cell lysate Loading : 20 microg per lane Dilution : 1:2000
WB analysis of various samples using GTX82503 EZH2 antibody. Lane 1: HeLa whole cell lysate Lane 2: Jurkat whole cell lysate Lane 3: MCF-7 whole cell lysate Lane 4: Neuro-2a whole cell lysate Lane 5: T47D whole cell lysate Loading : 20 microg per lane Dilution : 1:2000

EZH2 antibody

GTX82503
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetEZH2
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Overview

  • Supplier
    GeneTex
  • Product Name
    EZH2 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000. ICC/IF: 1:25. FACS: 1:25. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID2146
  • Target name
    EZH2
  • Target description
    enhancer of zeste 2 polycomb repressive complex 2 subunit
  • Target synonyms
    ENX-1, ENX1, EZH2b, KMT6, KMT6A, WVS, WVS2, histone-lysine N-methyltransferase EZH2, enhancer of zeste homolog 2, lysine N-methyltransferase 6
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ15910
  • Protein Name
    Histone-lysine N-methyltransferase EZH2
  • Scientific Description
    This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Qian X, Zhang Y. EZH2 enhances proliferation and migration of trophoblast cell lines by blocking GADD45A-mediated p38/MAPK signaling pathway. Bioengineered. 2022,13(5):12583-12597. doi: 10.1080/21655979.2022.2074620
    Read this paper
  • Fathy A, Abdelrahman AE. EZH2, Endothelin-1, and CD34 as Biomarkers of Aggressive Cervical Squamous Cell Carcinoma: An Immunohistochemical Study. Turk Patoloji Derg. 2018,34(2):150-57. doi: 10.5146/tjpath.2018.01425
    Read this paper
  • Hsieh YY, Lo HL, Yang PM. EZH2 inhibitors transcriptionally upregulate cytotoxic autophagy and cytoprotective unfolded protein response in human colorectal cancer cells. Am J Cancer Res. 2016,6(8):1661-80.
    Read this paper

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