ProductsBack/Ezrin antibody [N2C2], Internal

Ezrin antibody [N2C2], Internal

Name: Ezrin antibody [N2C2], Internal
SKU: GTX111709_G10
Availability: BackOrder

GTX111709

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman, Mouse, Rat, Zebra Fish

TargetEZR

Overview

Supplier
GeneTex
Product Name
Ezrin antibody [N2C2], Internal
Delivery Days Customer
9
Application Supplier Note
WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1.84 mg/ml
Conjugate
Unconjugated
Gene ID7430
Target name
EZR
Target description
ezrin
Target synonyms
CVIL, CVL, HEL-S-105, VIL2, ezrin, cytovillin 2, epididymis secretory protein Li 105, p81, villin 2 (ezrin)
Host
Rabbit
Isotype
IgG
Protein IDP15311
Protein Name
Ezrin
Scientific Description
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq]
Reactivity
Human, Mouse, Rat, Zebra Fish
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Liang Y, Tan F, Sun X, et al. Aberrant Retinal Pigment Epithelial Cells Derived from Induced Pluripotent Stem Cells of a Retinitis Pigmentosa Patient with the PRPF6 Mutation. Int J Mol Sci. 2022,23(16). doi: 10.3390/ijms23169049
Read this paper
Wang SA, Young MJ, Wang YC, et al. USP24 promotes drug resistance during cancer therapy. Cell Death Differ. 2021,28(9):2690-2707. doi: 10.1038/s41418-021-00778-z
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Chang SJ, Liao EC, Yeo HY, et al. Proteomic investigating the cooperative lethal effect of EGFR and MDM2 inhibitors on ovarian carcinoma. Arch Biochem Biophys. 2018,647:10-32. doi: 10.1016/j.abb.2018.04.004
Read this paper
Sundararaman B, Zhan L, Blue SM, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016,61(6):903-13. doi: 10.1016/j.molcel.2016.02.012
Read this paper
May EW, Lin ST, Lin CC, et al. Identification of up- and down-regulated proteins in doxorubicin-resistant uterine cancer cells: reticulocalbin-1 plays a key role in the development of doxorubicin-associated resistance. Pharmacol Res. 2014,90:1-17. doi: 10.1016/j.phrs.2014.08.007
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Law CH, Li JM, Chou HC, et al. Hyaluronic acid-dependent protection in H9C2 cardiomyocytes: a cell model of heart ischemia-reperfusion injury and treatment. Toxicology. 2013,303:54-71. doi: 10.1016/j.tox.2012.11.006
Read this paper