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F-1 [2244775-31-1]

F-1 [2244775-31-1]

T11254
TargetMol Chemicals
CAS Number2244775-31-1
Product group Chemicals
Estimated Purity97.66%
Molecular Weight519.02
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    F-1 [2244775-31-1]
  • Delivery Days Customer
    4
  • CAS Number
    2244775-31-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    F-1
  • Estimated Purity
    97.66%
  • Molecular Formula
    C22H27ClN8O3S
  • Molecular Weight
    519.02
  • Scientific Description
    F-1 is IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively. F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways.
  • Shelf life instruction
    3 years
  • SMILES
    COc1nc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCN(C)CC1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200