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Factor V Heavy chain antibody [B10]

GTX21015
GeneTex
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetF5
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Overview

  • Supplier
    GeneTex
  • Product Name
    Factor V Heavy chain antibody [B10]
  • Delivery Days Customer
    9
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    B10
  • Conjugate
    Unconjugated
  • Gene ID2153
  • Target name
    F5
  • Target description
    coagulation factor V
  • Target synonyms
    activated protein c cofactor; coagulation factor V; coagulation factor V (proaccelerin, labile factor); coagulation factor V jinjiang A2 domain; factor V Leiden; FVL; PCCF; RPRGL1; THPH2
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP12259
  • Protein Name
    Coagulation factor V
  • Scientific Description
    This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance. [provided by RefSeq, Oct 2008]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Effect of blood flow on platelets, leukocytes, and extracellular vesicles in thrombosis of simulated neonatal extracorporeal circulation. Meyer AD et al., 2020 Feb, J Thromb Haemost
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  • Biology of human megakaryocyte factor V.
    Read more