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IHC-P analysis of human brain tissue using GTX85231 FAM59A antibody. Working concentration : 5 microg/ml
IHC-P analysis of human brain tissue using GTX85231 FAM59A antibody. Working concentration : 5 microg/ml
IHC-P analysis of human brain tissue using GTX85231 FAM59A antibody. Working concentration : 5 microg/ml

FAM59A antibody

Research Use Only
GTX85231
GeneTex
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGAREM1
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    FAM59A antibody
  • Delivery Days Customer
    9
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID64762
  • Target name
    GAREM1
  • Target description
    GRB2 associated regulator of MAPK1 subtype 1
  • Target synonyms
    C18orf11; FAM59A; family with sequence similarity 59, member A; GAREM; Gm944; GRB2 associated regulator of MAPK1 1; GRB2 associated, regulator of MAPK1; Grb2-associated and regulator of Erk/MAPK; GRB2-associated and regulator of MAPK protein 1; GRB2-associated and regulator of MAPK1; protein FAM59A
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    FAM59A, also known as GAREM, was initially identified through a mass spectroscoptic method that measures different phosphotyrosine states of proteins in response to different cell stimuli. FAM59A is a downstream molecule in the EGF signaling pathway that is tyrosine-phosphorylated, and this phosphorylation is needed for the binding of Grb2, an adaptor protein crucial to the transduction of growth signals from the plasma membrane to the nucleus. ERK activation in response to EGF stimulation is regulated by FAM59A in COS-7 and HeLa cells, and the overexpression of FAM59A stimulated cell proliferation and colony formation in soft agar, suggesting that FAM59A might be a critical protein with roles in ligand-mediated signaling pathway of the EGF receptor and the tumorigenesis of cells.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203