IHC-P analysis of rat kidney tissue section using GTX09129 Fas antibody [GT1169]. Dlution : 1:100
![WB analysis of Wild-type (WT) and Fas knockout (KO) HeLa cell extracts using GTX09129 Fas antibody [GT1169]. Dilution : 1:1000 Loading : 25microg](https://www.genetex.com/upload/website/prouct_img/normal/GTX09129/GTX09129_20200327_WB_1_w_23053123_300.webp "WB analysis of Wild-type (WT) and Fas knockout (KO) HeLa cell extracts using GTX09129 Fas antibody [GT1169]. Dilution : 1:1000 Loading : 25microg")
![WB analysis of Jurkat and HepG2 whole cell lysates using GTX09129 Fas antibody [GT1169]. Dilution : 1:1000 Loading : 25microg](https://www.genetex.com/upload/website/prouct_img/normal/GTX09129/GTX09129_20200327_WB_2_w_23053123_361.webp "WB analysis of Jurkat and HepG2 whole cell lysates using GTX09129 Fas antibody [GT1169]. Dilution : 1:1000 Loading : 25microg")
![Various whole cell extracts (30 microg) were separated by 10% SDS-PAGE, and the membrane was blotted with Fas antibody [GT1169] (GTX09129) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX09129/GTX09129_40000000061_20200306_WB_1_w_23053123_433.webp "Various whole cell extracts (30 microg) were separated by 10% SDS-PAGE, and the membrane was blotted with Fas antibody [GT1169] (GTX09129) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.")
![Various whole cell extracts (30 microg) were separated by 10% SDS-PAGE, and the membrane was blotted with Fas antibody [GT1169] (GTX09129) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX09129/GTX09129_40000000061_20200306_WB_w_23053123_690.webp "Various whole cell extracts (30 microg) were separated by 10% SDS-PAGE, and the membrane was blotted with Fas antibody [GT1169] (GTX09129) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.")
IHC-P analysis of rat kidney tissue section using GTX09129 Fas antibody [GT1169]. Dlution : 1:100
Fas antibody [GT1169]
GTX09129
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetFAS
Overview
- SupplierGeneTex
- Product NameFas antibody [GT1169] - Recombinant antibody, KO/KD Validated
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT1169
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID355
- Target nameFAS
- Target descriptionFas cell surface death receptor
- Target synonymsALPS1A; APO-1; APO-1 cell surface antigen; apoptosis antigen 1; apoptosis signaling receptor FAS; apoptosis-mediating surface antigen FAS; APT1; CD95; CD95 antigen; Fas (TNF receptor superfamily, member 6); Fas AMA; FAS1; FASLG receptor; FASTM; mutant tumor necrosis receptor superfamily member 6; TNF receptor superfamily member 6; TNFRSF6; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily, member 6
- HostRabbit
- IsotypeIgG
- Protein IDP25445
- Protein NameTumor necrosis factor receptor superfamily member 6
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. [provided by RefSeq, Mar 2011]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203