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FACS analysis of Fas Ligand transfected CHO cells using GTX42345 Fas Ligand antibody [10F2] (Low endotoxin, azide free).
FACS analysis of Fas Ligand transfected CHO cells using GTX42345 Fas Ligand antibody [10F2] (Low endotoxin, azide free).
FACS analysis of Fas Ligand transfected CHO cells using GTX42345 Fas Ligand antibody [10F2] (Low endotoxin, azide free).

Fas Ligand antibody [10F2] (Low endotoxin, azide free)

GTX42345
GeneTex
ApplicationsFlow Cytometry, ImmunoPrecipitation, ELISA, Neutralisation/Blocking, Other Application
Product group Antibodies
TargetFASLG
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Overview

  • Supplier
    GeneTex
  • Product Name
    Fas Ligand antibody [10F2] (Low endotoxin, azide free)
  • Delivery Days Customer
    9
  • Application Supplier Note
    FACS: 1/25-1/50. Neutralizing/Inhibition: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoPrecipitation, ELISA, Neutralisation/Blocking, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    10F2
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID356
  • Target name
    FASLG
  • Target description
    Fas ligand
  • Target synonyms
    ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6, TNLG1A, tumor necrosis factor ligand superfamily member 6, CD95 ligand, Fas ligand (TNF superfamily, member 6), apoptosis (APO-1) antigen ligand 1, apoptosis antigen ligand, fas antigen ligand, mutant tumor necrosis factor family member 6, tumor necrosis factor ligand 1A
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP48023
  • Protein Name
    Tumor necrosis factor ligand superfamily member 6
  • Scientific Description
    This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Rabbit antithymocyte globulin induces human lymphocyte activation, proliferation, and apoptosis in the absence of complement: an experimental study. Tan X et al., 2021 May, Transpl Int
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  • Fas/FasL interaction mediates imbalanced cytokine/cytotoxicity responses of iNKT cells against Jurkat cells. Dou R et al., 2018 Jul, Mol Immunol
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