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Fasudil (dihydrochloride)

HY-10341C
MedChem Express
CAS Number203911-27-7
Product group Chemicals
Estimated Purity99.98
Molecular Weight364.29
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Fasudil (dihydrochloride)
  • Delivery Days Customer
    10
  • CAS Number
    203911-27-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.98
  • Molecular Formula
    C14H19Cl2N3O2S
  • Molecular Weight
    364.29
  • Scientific Description
    Fasudil (HA-1077; AT877) dihydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 microM for ROCK1, IC50s of 0.158 microM and 4.58 microM, 12.30 microM, 1.650 microM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil dihydrochloride is also a potent Ca2+ channel antagonist and vasodilator[1][2][3].
  • SMILES
    O=S(C1=CC=CC2=C1C=CN=C2)(N3CCNCCC3)=O.[H]Cl.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200