Bio-Connect

FBXL3 antibody

Research Use Only
GTX110755
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetFBXL3
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Overview

  • Supplier
    GeneTex
  • Product Name
    FBXL3 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.41 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID26224
  • Target name
    FBXL3
  • Target description
    F-box and leucine rich repeat protein 3
  • Target synonyms
    FBL3; FBL3A; F-box and leucine-rich repeat protein 3A; F-box protein Fbl3a; F-box/LRR-repeat protein 3; F-box/LRR-repeat protein 3A; FBXL3A; IDDSFAS
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9UKT7
  • Protein Name
    F-box/LRR-repeat protein 3
  • Scientific Description
    This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • The beta-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor. Xu J et al., 2017 Jan 16, Nat Commun
    Read more
  • Highly Efficient Genome Editing via CRISPR/Cas9 to Create Clock Gene Knockout Cells. Korge S et al., 2015 Oct, J Biol Rhythms
    Read more