FBXL3 antibody
GTX110755
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetFBXL3
Overview
- SupplierGeneTex
- Product NameFBXL3 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.41 mg/ml
- ConjugateUnconjugated
- Gene ID26224
- Target nameFBXL3
- Target descriptionF-box and leucine rich repeat protein 3
- Target synonymsFBL3, FBL3A, FBXL3A, IDDSFAS, F-box/LRR-repeat protein 3, F-box and leucine-rich repeat protein 3A, F-box protein Fbl3a, F-box/LRR-repeat protein 3A
- HostRabbit
- IsotypeIgG
- Protein IDQ9UKT7
- Protein NameF-box/LRR-repeat protein 3
- Scientific DescriptionThis gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Xu J, Zhou W, Yang F, et al. The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor. Nat Commun. 2017,8:14002. doi: 10.1038/ncomms14002Read this paper
- Korge S, Grudziecki A, Kramer A. Highly Efficient Genome Editing via CRISPR/Cas9 to Create Clock Gene Knockout Cells. J Biol Rhythms. 2015,30(5):389-95. doi: 10.1177/0748730415597519Read this paper






