IHC-P analysis of mouse muscle tissue using GTX00810 FBXO32 Antibody. Antigen retrieval : Heat mediated antigen retrieval step in citrate buffer Dilution : 1:100
IHC-P analysis of mouse muscle tissue using GTX00810 FBXO32 Antibody. Antigen retrieval : Heat mediated antigen retrieval step in citrate buffer Dilution : 1:100
FBXO32 antibody
GTX00810
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetFBXO32
Overview
- SupplierGeneTex
- Product NameFBXO32 antibody
- Delivery Days Customer9
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID114907
- Target nameFBXO32
- Target descriptionF-box protein 32
- Target synonymsatrogin 1; F-box only protein 32; Fbx32; MAFbx; muscle atrophy F-box protein
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203