FDFT1 antibody [N1C3]
GTX108885
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetFDFT1
Overview
- SupplierGeneTex
- Product NameFDFT1 antibody [N1C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.97 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID2222
- Target nameFDFT1
- Target descriptionfarnesyl-diphosphate farnesyltransferase 1
- Target synonymsDGPT; ERG9; FPP:FPP farnesyltransferase; presqualene-di-diphosphate synthase; SQS; SQSD; squalene synthase; squalene synthetase; SS
- HostRabbit
- IsotypeIgG
- Protein IDP37268
- Protein NameSqualene synthase
- Scientific DescriptionThis gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Viral MicroRNAs Repress the Cholesterol Pathway, and 25-Hydroxycholesterol Inhibits Infection. Serquina AKP et al., 2017 Jul 11, MBioRead more
- Cellular cholesterol accumulation modulates high fat high sucrose (HFHS) diet-induced ER stress and hepatic inflammasome activation in the development of non-alcoholic steatohepatitis. Bashiri A et al., 2016 Jul, Biochim Biophys ActaRead more