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FDFT1 antibody [N1C3]

Research Use Only
GTX108885
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetFDFT1
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Overview

  • Supplier
    GeneTex
  • Product Name
    FDFT1 antibody [N1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.97 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID2222
  • Target name
    FDFT1
  • Target description
    farnesyl-diphosphate farnesyltransferase 1
  • Target synonyms
    DGPT; ERG9; FPP:FPP farnesyltransferase; presqualene-di-diphosphate synthase; SQS; SQSD; squalene synthase; squalene synthetase; SS
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP37268
  • Protein Name
    Squalene synthase
  • Scientific Description
    This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Viral MicroRNAs Repress the Cholesterol Pathway, and 25-Hydroxycholesterol Inhibits Infection. Serquina AKP et al., 2017 Jul 11, MBio
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  • Cellular cholesterol accumulation modulates high fat high sucrose (HFHS) diet-induced ER stress and hepatic inflammasome activation in the development of non-alcoholic steatohepatitis. Bashiri A et al., 2016 Jul, Biochim Biophys Acta
    Read more