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ProductsBack/FDFT1 antibody [N1C3]

FDFT1 antibody [N1C3]

GTX108885

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetFDFT1

Overview

Supplier
GeneTex
Product Name
FDFT1 antibody [N1C3]
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.97 mg/ml
Conjugate
Unconjugated
Gene ID2222
Target name
FDFT1
Target description
farnesyl-diphosphate farnesyltransferase 1
Target synonyms
DGPT, ERG9, SQS, SQSD, SS, squalene synthase, FPP:FPP farnesyltransferase, presqualene-di-diphosphate synthase, squalene synthetase
Host
Rabbit
Isotype
IgG
Protein IDP37268
Protein Name
Squalene synthase
Scientific Description
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Serquiña AKP, Kambach DM, Sarker O, et al. Viral MicroRNAs Repress the Cholesterol Pathway, and 25-Hydroxycholesterol Inhibits Infection. mBio. 2017,8(4). doi: 10.1128/mBio.00576-17
Read this paper
Bashiri A, Nesan D, Tavallaee G, et al. Cellular cholesterol accumulation modulates high fat high sucrose (HFHS) diet-induced ER stress and hepatic inflammasome activation in the development of non-alcoholic steatohepatitis. Biochim Biophys Acta. 2016,1861(7):594-605. doi: 10.1016/j.bbalip.2016.04.005
Read this paper

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