FDFT1 antibody [N2C3]
GTX104091
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetFDFT1
Overview
- SupplierGeneTex
- Product NameFDFT1 antibody [N2C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.55 mg/ml
- ConjugateUnconjugated
- Gene ID2222
- Target nameFDFT1
- Target descriptionfarnesyl-diphosphate farnesyltransferase 1
- Target synonymsDGPT, ERG9, SQS, SQSD, SS, squalene synthase, FPP:FPP farnesyltransferase, presqualene-di-diphosphate synthase, squalene synthetase
- HostRabbit
- IsotypeIgG
- Protein IDP37268
- Protein NameSqualene synthase
- Scientific DescriptionThis gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Chang YC, Li CH, Chan MH, et al. Regorafenib inhibits epithelial-mesenchymal transition and suppresses cholangiocarcinoma metastasis via YAP1-AREG axis. Cell Death Dis. 2022,13(4):391. doi: 10.1038/s41419-022-04816-7Read this paper
- Yang YF, Chang YC, Jan YH, et al. Squalene synthase promotes the invasion of lung cancer cells via the osteopontin/ERK pathway. Oncogenesis. 2020,9(8):78. doi: 10.1038/s41389-020-00262-2Read this paper




