FDFT1 antibody [N2C3]
GTX104091
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetFDFT1
Overview
- SupplierGeneTex
- Product NameFDFT1 antibody [N2C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.55 mg/ml
- ConjugateUnconjugated
- Gene ID2222
- Target nameFDFT1
- Target descriptionfarnesyl-diphosphate farnesyltransferase 1
- Target synonymsDGPT; ERG9; FPP:FPP farnesyltransferase; presqualene-di-diphosphate synthase; SQS; SQSD; squalene synthase; squalene synthetase; SS
- HostRabbit
- IsotypeIgG
- Protein IDP37268
- Protein NameSqualene synthase
- Scientific DescriptionThis gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Regorafenib inhibits epithelial-mesenchymal transition and suppresses cholangiocarcinoma metastasis via YAP1-AREG axis. Chang YC et al., 2022 Apr 21, Cell Death DisRead more
- Squalene synthase promotes the invasion of lung cancer cells via the osteopontin/ERK pathway. Yang YF et al., 2020 Aug 29, OncogenesisRead more
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