FDPS antibody [N1C3]

GeneTex

FDPS antibody [N1C3]

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1.35 mg/ml

Unconjugated

FDPS

farnesyl diphosphate synthase

FPPS, FPS, POROK9, farnesyl pyrophosphate synthase, (2E,6E)-farnesyl diphosphate synthase, FPP synthase, FPP synthetase, farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase

Rabbit

IgG

Farnesyl pyrophosphate synthase

This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203