FHIT antibody [GT1240]

GeneTex

FHIT antibody [GT1240]

9

WB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Monoclonal

GT1240

1.59 mg/ml

Unconjugated

FHIT

fragile histidine triad diadenosine triphosphatase

AP3A hydrolase; AP3Aase; bis(5'-adenosyl)-triphosphatase; diadenosine 5',5'''-P1,P3-triphosphate hydrolase; dinucleosidetriphosphatase; FRA3B

Rabbit

IgG

Bis(5'-adenosyl)-triphosphatase

The protein encoded by this gene is a P1-P3-bis(5-adenosyl) triphosphate hydrolase involved in purine metabolism. This gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. The encoded protein is also a tumor suppressor, as loss of its activity results in replication stress and DNA damage. [provided by RefSeq, Aug 2017]

-20°C,2°C to 8°C

12352203