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Fibrinogen beta antibody [C1C3]

GTX113694
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
DownloadDatasheet
Product group Antibodies
TargetFGB
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Overview

  • Supplier
    GeneTex
  • Product Name
    Fibrinogen beta antibody [C1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:5000-1:50000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.94 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2244
  • Target name
    FGB
  • Target description
    fibrinogen beta chain
  • Target synonyms
    beta-fibrinogen; epididymis secretory sperm binding protein Li 78p; fibrinogen beta chain; fibrinogen, B beta polypeptide; HEL-S-78p
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP02675
  • Protein Name
    Fibrinogen beta chain
  • Scientific Description
    The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Dengue virus-induced autoantibodies bind to plasminogen and enhance its activation. Chuang YC et al., 2011 Dec 15, J Immunol
    Read more

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