Filgotinib
HY-18300
CAS Number1206161-97-8
Product group Chemicals
Estimated Purity99.44
Molecular Weight425.50
Overview
- SupplierMedChem Express
- Product NameFilgotinib [1206161-97-8]
- Delivery Days Customer10
- CAS Number1206161-97-8
- CertificationResearch Use Only
- Estimated Purity99.44
- Molecular FormulaC21H23N5O3S
- Molecular Weight425.50
- Scientific DescriptionFilgotinib (GLPG0634) is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. Filgotinib can effectively inhibit the activities of JAK1 , JAK2 , JAK3 and TYK2 with IC 50 values of 10 nM, 28 nM, 810 nM and 116 nM, respectively. Filgotinib also inhibits HIV-1 driven gene transcription and reduces proliferation of HIV-1 infected cells. Filgotinib can be used in the study of rheumatoid arthritis and inflammatory bowel disease [1] [2] [3] .
- SMILESO=C(C1CC1)NC2=NN3C(C4=CC=C(CN5CCS(CC5)(=O)=O)C=C4)=CC=CC3=N2
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200