Firsocostat [1434635-54-7]
T7184
CAS Number1434635-54-7
Product group Chemicals
Estimated Purity99.01%
Molecular Weight569.63
Overview
- SupplierTargetMol Chemicals
- Product NameFirsocostat [1434635-54-7]
- Delivery Days Customer4
- CAS Number1434635-54-7
- CertificationResearch Use Only
- Chemical NameFirsocostat
- Estimated Purity99.01%
- Molecular FormulaC28H31N3O8S
- Molecular Weight569.63
- Scientific DescriptionFirsocostat (GS-0976) is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively)
- Shelf life instruction3 years
- SMILESCOc1ccccc1[C@H](Cn1c2sc(c(C)c2c(=O)n(c1=O)C(C)(C)C(O)=O)-c1ncco1)OC1CCOCC1
- Storage Instruction-20°C
- UNSPSC12352200
References
- Harriman G, Greenwood J, Bhat S, et al. Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats. Proc Natl Acad Sci U S A. 2016,113(13):E1796-805. doi: 10.1073/pnas.1520686113Read this paper
MSDS
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