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Firsocostat [1434635-54-7]

Firsocostat [1434635-54-7]

T7184
TargetMol Chemicals
CAS Number1434635-54-7
Product group Chemicals
Estimated Purity99.01%
Molecular Weight569.63
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Firsocostat [1434635-54-7]
  • Delivery Days Customer
    4
  • CAS Number
    1434635-54-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Firsocostat
  • Estimated Purity
    99.01%
  • Molecular Formula
    C28H31N3O8S
  • Molecular Weight
    569.63
  • Scientific Description
    Firsocostat (GS-0976) is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively)
  • Shelf life instruction
    3 years
  • SMILES
    COc1ccccc1[C@H](Cn1c2sc(c(C)c2c(=O)n(c1=O)C(C)(C)C(O)=O)-c1ncco1)OC1CCOCC1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats. Harriman G et al., 2016 Mar 29, Proc Natl Acad Sci U S A
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