FLAP antibody, Internal

GeneTex

FLAP antibody, Internal

9

WB: 0.1-0.3microg/ml. IHC-P: 3-6microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

ALOX5AP

arachidonate 5-lipoxygenase activating protein

FLAP, arachidonate 5-lipoxygenase-activating protein, MK-886-binding protein

Goat

IgG

Arachidonate 5-lipoxygenase-activating protein

This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]

-20°C or -80°C,2°C to 8°C

12352203