Flavokawain B

MedChem Express

Flavokawain B [1775-97-9]

9

1775-97-9

Research Use Only

99.99

C17H16O4

284.31

Flavokawain B (Flavokavain B) is an orally active chalcone. Flavokawain B results in activation of caspase-9, -3 and -8 , cleavage of PARP . Flavokawain B down-regulates Bcl-2 with concomitant increase in Bax level. Flavokawain B inhibits NF-kappaB , PI3K/Akt and MAPK signaling pathway. Flavokawain B exhibits Apoptotic effects. Flavokawain B inhibits MMP-9 and promotes ROS generation. Flavokawain B inhibits multiple tumors and inflammation [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11] [12] [13] .

O=C(C1=C(OC)C=C(OC)C=C1O)/C=C/C2=CC=CC=C2

2°C to 8°C

12352200