Flavokawain B [1775-97-9]

MedChem Express

Flavokawain B [1775-97-9]

9

1775-97-9

Research Use Only

99.99

C17H16O4

284.31

Flavokawain B (Flavokavain B) is an orally active chalcone. Flavokawain B results in activation of caspase-9, -3 and -8, cleavage of PARP. Flavokawain B down-regulates Bcl-2 with concomitant increase in Bax level. Flavokawain B inhibits NF-kappaB, PI3K/Akt and MAPK signaling pathway. Flavokawain B exhibits Apoptotic effects. Flavokawain B inhibits MMP-9 and promotes ROS generation. Flavokawain B inhibits multiple tumors and inflammation[1][2][3][4][5][6][7][8][9][10][11][12][13].

O=C(C1=C(OC)C=C(OC)C=C1O)/C=C/C2=CC=CC=C2

2°C to 8°C

12352200