Fludarabine triphosphate trisodium

TargetMol Chemicals

Fludarabine triphosphate trisodium

999

Chemical

Research Use Only

Fludarabine triphosphate trisodium

C10H12FN5Na3O13P3

591.12

Fludarabine triphosphate (F-ara-ATP) trisodium, the principal metabolite of Fludarabine, is a potent, noncompetitive, and specific inhibitor of DNA primase with an IC50 value of 2.3 microM and a Ki of 6.1 microM. It obstructs DNA synthesis by hindering DNA primase and primer RNA formation, while also inhibiting ribonucleotide reductase and DNA polymerase activities, effectively inducing cellular apoptosis [1] [2].

3 years

-20°C

12352200