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ProductsBack/Fludarabine triphosphate trisodium

Fludarabine triphosphate trisodium

T74088

Molecular Weight591.12

Product group Chemicals

Overview

Supplier
TargetMol Chemicals
Product Name
Fludarabine triphosphate trisodium
Delivery Days Customer
999
Certification
Research Use Only
Chemical Name
Fludarabine triphosphate trisodium
Molecular Formula
C10H12FN5Na3O13P3
Molecular Weight
591.12
Scientific Description
Fludarabine triphosphate (F-ara-ATP) trisodium, the principal metabolite of Fludarabine, is a potent, noncompetitive, and specific inhibitor of DNA primase with an IC50 value of 2.3 microM and a Ki of 6.1 microM. It obstructs DNA synthesis by hindering DNA primase and primer RNA formation, while also inhibiting ribonucleotide reductase and DNA polymerase activities, effectively inducing cellular apoptosis [1] [2].
Shelf life instruction
3 years
Storage Instruction
-20°C
UNSPSC
12352200

MSDS

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