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Fluzoparib (SHR3162)

M10445
AbMole BioScience
CAS Number1358715-18-0
Product group Chemicals
Molecular Weight472.40
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Fluzoparib (SHR3162)
  • Delivery Days Customer
    9
  • CAS Number
    1358715-18-0
  • Certification
    Research Use Only
  • Molecular Formula
    C22H16F4N6O2
  • Molecular Weight
    472.40
  • Scientific Description
    Fluzoparib (SHR3162) is an effective oral active PARP1 inhibitor (IC50=1.46±0.72 nM) with superior antitumor activity. Fluzoparib selectively inhibited the proliferation of homologous recombination repair (HR) deficient cells and sensitized HR deficient cells to cytotoxic drugs. Fluzoparib has good pharmacokinetic properties in vivo and can be used in cancer research.
  • SMILES
    FC1=CC=C(CC2=NNC(=O)C3=C2C=CC=C3)C=C1C(=O)N4CC[N]5N=C(N=C5C4)C(F)(F)F
  • UNSPSC
    12352200

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