FM-479 [2226521-64-6]

AbMole BioScience

FM-479 [2226521-64-6]

7

2226521-64-6

Research Use Only

C25H26N6O2

442.51

Fm-479 was a negative control of FM-381 and showed no activity against JAK3 or other kinases. Fm-381 is a potent covalent reversible inhibitor of JAK3 targeting unique Cys909. For JAK3, FM-381 was 410, 2700 and 3600 times more selective than JAK1, JAK2 and TYK2 with IC50 of 127 pM.

-20°C

12161500