FMRP antibody [4G9]

GeneTex

FMRP antibody [4G9]

9

WB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. IHC-P: 1/200 - 1/1000. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

4G9

Unconjugated

FMR1

FMRP translational regulator 1

FMRP; fragile X mental retardation 1; fragile X mental retardation protein 1; FRAXA; POF; POF1; synaptic functional regulator FMR1; truncated FMRP

Mouse

IgG1

Synaptic functional regulator FMR1

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5 UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203