Fumarate hydratase antibody [GT548]

GeneTex

Fumarate hydratase antibody [GT548]

9

Western Blot

Research Use Only

Monoclonal

GT548

1 mg/ml

Unconjugated

FH

fumarate hydratase

epididymis secretory sperm binding protein; FMRD; fumarase; fumarate hydratase, mitochondrial; HLRCC; HsFH; LRCC; MCL; MCUL1

Mouse

IgG2b

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008]

Human, Mouse, Rat

2°C to 8°C,-20°C or -80°C

12352203