Furin antibody [C3], C-term

GeneTex

Furin antibody [C3], C-term

9

ELISA

Research Use Only

Polyclonal

0.67 mg/ml

Unconjugated

FURIN

furin, paired basic amino acid cleaving enzyme

dibasic processing enzyme; FES upstream region; FUR; furin; furin, membrane associated receptor protein; PACE; paired basic amino acid residue-cleaving enzyme; PCSK3; proprotein convertase subtilisin/kexin 3; proprotein convertase subtilisin/kexin type 3; SPC1; subtilisin-like proprotein convertase 1

Rabbit

IgG

Furin

The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can efficiently cleave precursor proteins at their paired basic amino acid processing sites. Some of its substrates are: proparathyroid hormone, transforming growth factor beta 1 precursor, proalbumin, pro-beta-secretase, membrane type-1 matrix metalloproteinase, beta subunit of pro-nerve growth factor and von Willebrand factor. It is also thought to be one of the proteases responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene is thought to play a role in tumor progression. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq]

Human

-20°C or -80°C,2°C to 8°C

12352203