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FzM1 [1680196-54-6]

FzM1 [1680196-54-6]

T24076
TargetMol Chemicals
CAS Number1680196-54-6
DownloadMSDS
Product group Chemicals
Estimated Purity99.89%
Molecular Weight360.43
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    FzM1 [1680196-54-6]
  • Delivery Days Customer
    4
  • CAS Number
    1680196-54-6
  • Category Supplier
    Chemical
  • Chemical Name
    FzM1
  • Estimated Purity
    99.89%
  • Molecular Formula
    C21H16N2O2S
  • Molecular Weight
    360.43
  • Scientific Description
    FzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=-6.2) by binding to an allosteric site on intracellular loop 3 (ICL3) of FZD4. This interaction changes the receptors conformation and inhibits the WNT/beta-catenin signaling pathway.
  • Shelf life instruction
    3 years
  • SMILES
    Oc1cc(NC(=O)Nc2ccc3ccccc3c2)cc(c1)-c1cccs1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200