![FzM1 [1680196-54-6] FzM1 [1680196-54-6]](https://www.targetmol.com/group3/M00/37/33/CgoaEGaySW-ERKloAAAAAPVHyXY252.png)
FzM1 [1680196-54-6]

T24076
CAS Number1680196-54-6
Product group Chemicals
Estimated Purity99.89%
Molecular Weight360.43
Overview
- SupplierTargetMol Chemicals
- Product NameFzM1 [1680196-54-6]
- Delivery Days Customer4
- CAS Number1680196-54-6
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameFzM1
- Estimated Purity99.89%
- Molecular FormulaC21H16N2O2S
- Molecular Weight360.43
- Scientific DescriptionFzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=-6.2) by binding to an allosteric site on intracellular loop 3 (ICL3) of FZD4. This interaction changes the receptors conformation and inhibits the WNT/beta-catenin signaling pathway.
- Shelf life instruction3 years
- SMILESOc1cc(NC(=O)Nc2ccc3ccccc3c2)cc(c1)-c1cccs1
- Storage Instruction-20°C
- UNSPSC12352200