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ProductsBack/FZR1 Antibody
Western blot All lanes: FZR1 antibody at 6ug/ml Lane 1: Hela whole cell lysate Lane 2: Jurkat whole cell lysate Lane 3: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 56, 55, 45 kDa Observed band size: 56 kDa
Western blot All lanes: FZR1 antibody at 6ug/ml Lane 1: Hela whole cell lysate Lane 2: Jurkat whole cell lysate Lane 3: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 56, 55, 45 kDa Observed band size: 56 kDa
Western blot All lanes: FZR1 antibody at 6ug/ml Lane 1: Hela whole cell lysate Lane 2: Jurkat whole cell lysate Lane 3: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 56, 55, 45 kDa Observed band size: 56 kDa

FZR1 Antibody

CSB-PA892473LA01HU
Cusabio
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetFZR1
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Overview

  • Supplier
    Cusabio
  • Product Name
    FZR1 Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID51343
  • Target name
    FZR1
  • Target description
    fizzy and cell division cycle 20 related 1
  • Target synonyms
    CDC20C, CDH1, DEE109, FZR, FZR2, HCDH, HCDH1, fizzy-related protein homolog, CDC20 homolog 1, CDC20-like 1b, CDC20-like protein 1, cdh1/Hct1 homolog, fizzy/cell division cycle 20 related 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9UM11
  • Protein Name
    Fizzy-related protein homolog
  • Scientific Description
    Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which confers substrate specificity upon the complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage checkpoint: its dephosphorylation and reassociation with the APC/C leads to the ubiquitination of PLK1, preventing entry into mitosis.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    41116161

FAQ

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