G3BP1 antibody
GTX112191
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetG3BP1
Overview
- SupplierGeneTex
- Product NameG3BP1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.35 mg/ml
- ConjugateUnconjugated
- Gene ID10146
- Target nameG3BP1
- Target descriptionG3BP stress granule assembly factor 1
- Target synonymsG3BP, HDH-VIII, ras GTPase-activating protein-binding protein 1, ATP-dependent DNA helicase VIII, DNA helicase VIII, G3BP-1, GAP SH3 domain-binding protein 1, GAP binding protein, GTPase activating protein (SH3 domain) binding protein 1, Ras-GTPase-activating protein SH3-domain-binding protein, RasGAP-associated endoribonuclease G3BP
- HostRabbit
- IsotypeIgG
- Protein IDQ13283
- Protein NameRas GTPase-activating protein-binding protein 1
- Scientific DescriptionThis gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Wen W, Zhao Q, Yin M, et al. Seneca Valley Virus 3C Protease Inhibits Stress Granule Formation by Disrupting eIF4GI-G3BP1 Interaction. Front Immunol. 2020,11:577838. doi: 10.3389/fimmu.2020.577838Read this paper
- Agote-Aran A, Schmucker S, Jerabkova K, et al. Spatial control of nucleoporin condensation by fragile X-related proteins. EMBO J. 2020,39(20):e104467. doi: 10.15252/embj.2020104467Read this paper
- Zhang LN, Zhao L, Yan XL, et al. Loss of G3BP1 suppresses proliferation, migration, and invasion of esophageal cancer cells via Wnt/β-catenin and PI3K/AKT signaling pathways. J Cell Physiol. 2019,234(11):20469-20484. doi: 10.1002/jcp.28648Read this paper
- Sundararaman B, Zhan L, Blue SM, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016,61(6):903-13. doi: 10.1016/j.molcel.2016.02.012Read this paper



