G6PD antibody [N3C3]
GTX101218
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetG6PD
Overview
- SupplierGeneTex
- Product NameG6PD antibody [N3C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.81 mg/ml
- ConjugateUnconjugated
- Gene ID2539
- Target nameG6PD
- Target descriptionglucose-6-phosphate dehydrogenase
- Target synonymsepididymis secretory sperm binding protein; G6PD1; glucose-6-phosphate 1-dehydrogenase
- HostRabbit
- IsotypeIgG
- Protein IDP11413
- Protein NameGlucose-6-phosphate 1-dehydrogenase
- Scientific DescriptionThis gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- mTOR inhibition downregulates glucose-6-phosphate dehydrogenase and induces ROS-dependent death in T-cell acute lymphoblastic leukemia cells. Silic-Benussi M et al., 2022 May, Redox BiolRead more
- Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by Onconase in A375 Melanoma Cells Correlates with the Downregulation of Specific Onco-Proteins. De Tomi E et al., 2022 Jan 31, Int J Mol SciRead more
- Proteomic analysis of Antrodia Cinnamomea-induced ER stress in liver cancer cells. Chen JF et al., 2020 Aug 5, J Pharm Biomed AnalRead more
- A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer. Choi EJ et al., 2017 Sep 14, OncogeneRead more