ProductsBack/G6PD antibody [N3C3]

G6PD antibody [N3C3]

Name: G6PD antibody [N3C3]
SKU: GTX101218_G10
Availability: BackOrder

GTX101218

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetG6PD

Overview

Supplier
GeneTex
Product Name
G6PD antibody [N3C3]
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.81 mg/ml
Conjugate
Unconjugated
Gene ID2539
Target name
G6PD
Target description
glucose-6-phosphate dehydrogenase
Target synonyms
epididymis secretory sperm binding protein; G6PD1; glucose-6-phosphate 1-dehydrogenase
Host
Rabbit
Isotype
IgG
Protein IDP11413
Protein Name
Glucose-6-phosphate 1-dehydrogenase
Scientific Description
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

mTOR inhibition downregulates glucose-6-phosphate dehydrogenase and induces ROS-dependent death in T-cell acute lymphoblastic leukemia cells. Silic-Benussi M et al., 2022 May, Redox Biol
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Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by Onconase in A375 Melanoma Cells Correlates with the Downregulation of Specific Onco-Proteins. De Tomi E et al., 2022 Jan 31, Int J Mol Sci
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Proteomic analysis of Antrodia Cinnamomea-induced ER stress in liver cancer cells. Chen JF et al., 2020 Aug 5, J Pharm Biomed Anal
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A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer. Choi EJ et al., 2017 Sep 14, Oncogene
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