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Immunohistochemical analysis of paraffin-embedded U87 xenograft, using G6PD(GTX101218) antibody at 1:300 dilution. Antigen Retrieval: Trilogy? (EDTA based, pH 8.0) buffer, 15min
Immunohistochemical analysis of paraffin-embedded U87 xenograft, using G6PD(GTX101218) antibody at 1:300 dilution.
 Antigen Retrieval: Trilogy? (EDTA based, pH 8.0) buffer, 15min
Immunohistochemical analysis of paraffin-embedded U87 xenograft, using G6PD(GTX101218) antibody at 1:300 dilution. Antigen Retrieval: Trilogy? (EDTA based, pH 8.0) buffer, 15min

G6PD antibody [N3C3]

GTX101218
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetG6PD
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Overview

  • Supplier
    GeneTex
  • Product Name
    G6PD antibody [N3C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.81 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2539
  • Target name
    G6PD
  • Target description
    glucose-6-phosphate dehydrogenase
  • Target synonyms
    CNSHA1, G6PD1, glucose-6-phosphate 1-dehydrogenase, epididymis secretory sperm binding protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP11413
  • Protein Name
    Glucose-6-phosphate 1-dehydrogenase
  • Scientific Description
    This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Silic-Benussi M, Sharova E, Ciccarese F, et al. mTOR inhibition downregulates glucose-6-phosphate dehydrogenase and induces ROS-dependent death in T-cell acute lymphoblastic leukemia cells. Redox Biol. 2022,51:102268. doi: 10.1016/j.redox.2022.102268
    Read this paper
  • De Tomi E, Campagnari R, Orlandi E, et al. Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by Onconase in A375 Melanoma Cells Correlates with the Downregulation of Specific Onco-Proteins. Int J Mol Sci. 2022,23(3). doi: 10.3390/ijms23031647
    Read this paper
  • Chen JF, Tsai YT, Lai YH, et al. Proteomic analysis of Antrodia Cinnamomea-induced ER stress in liver cancer cells. J Pharm Biomed Anal. 2020,187:113142. doi: 10.1016/j.jpba.2020.113142
    Read this paper
  • Choi EJ, Jung BJ, Lee SH, et al. A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer. Oncogene. 2017,36(37):5285-5295. doi: 10.1038/onc.2017.153
    Read this paper