Bio-Connect

G6PD antibody [N3C3]

GTX101218
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetG6PD
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Overview

  • Supplier
    GeneTex
  • Product Name
    G6PD antibody [N3C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.81 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2539
  • Target name
    G6PD
  • Target description
    glucose-6-phosphate dehydrogenase
  • Target synonyms
    epididymis secretory sperm binding protein; G6PD1; glucose-6-phosphate 1-dehydrogenase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP11413
  • Protein Name
    Glucose-6-phosphate 1-dehydrogenase
  • Scientific Description
    This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • mTOR inhibition downregulates glucose-6-phosphate dehydrogenase and induces ROS-dependent death in T-cell acute lymphoblastic leukemia cells. Silic-Benussi M et al., 2022 May, Redox Biol
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  • Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by Onconase in A375 Melanoma Cells Correlates with the Downregulation of Specific Onco-Proteins. De Tomi E et al., 2022 Jan 31, Int J Mol Sci
    Read more
  • Proteomic analysis of Antrodia Cinnamomea-induced ER stress in liver cancer cells. Chen JF et al., 2020 Aug 5, J Pharm Biomed Anal
    Read more
  • A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer. Choi EJ et al., 2017 Sep 14, Oncogene
    Read more