GA-017

Selleck Chemicals

GA-017

9

Research Use Only

...

GA-017 inhibits the serine/threonine protein kinases large tumor suppressor kinase 1/2 (LATS1/2), which exerts inhibitory with IC50s against LATS1 and 2 of 4.10+/-0.79 and 3.92+/-0.42 nM, respectively, and competitively inhibits LATS1 and 2 against ATP, with Ki (inhibition constant) values of 0.58+/-0.11 and 0.25+/-0.03 nM, respectively.

12352200