IHC-P analysis of human prostate cancer tissue using GTX46244 GADD45B antibody at 2microg/ml. Leica Bond antigen retrieval solution 1 (citrate buffer, pH 6.0) for 20 min at 99oC.
GADD45B antibody, Internal
GTX46244
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetGADD45B
Overview
- SupplierGeneTex
- Product NameGADD45B antibody, Internal
- Delivery Days Customer9
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID4616
- Target nameGADD45B
- Target descriptiongrowth arrest and DNA damage inducible beta
- Target synonymsGADD45BETA; growth arrest and DNA damage-inducible protein GADD45 beta; MYD118; myeloid differentiation primary response protein MyD118; negative growth regulatory protein MyD118
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203