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gamma-Secretase modulator 11 [2434630-29-0]

HY-147720
MedChem Express
CAS Number2434630-29-0
DownloadMSDS
Product group Chemicals
Molecular Weight484.50
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Overview

  • Supplier
    MedChem Express
  • Product Name
    gamma-Secretase modulator 11 [2434630-29-0]
  • Delivery Days Customer
    10
  • CAS Number
    2434630-29-0
  • Certification
    Research Use Only
  • Molecular Formula
    C28H22F2N4O2
  • Molecular Weight
    484.50
  • Scientific Description
    gamma-Secretase modulator 11 (1o) showed high potency in vitro and brain exposure, inducing brain a beta 42 levels were significantly reduced and showed undetectable inhibition of cytochrome P450 enzymes. In addition, compound 1o showed excellent anti cognitive deficit effect in AD model mice.
  • SMILES
    O=C(C1=NC=C(C2=C(C)N=C3C(OCC4=CC=C(C5=CC=C(F)C=C5)C=C4F)=CC=CN32)C=C1)NC
  • UNSPSC
    12131703

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