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gamma-Secretase modulator 12 [2204249-82-9]

gamma-Secretase modulator 12 [2204249-82-9]

T61881
TargetMol Chemicals
CAS Number2204249-82-9
Product group Chemicals
Molecular Weight397.47
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    gamma-Secretase modulator 12 [2204249-82-9]
  • Delivery Days Customer
    72
  • CAS Number
    2204249-82-9
  • Certification
    Research Use Only
  • Chemical Name
    gamma-Secretase modulator 12
  • Molecular Formula
    C25H23N3O2
  • Molecular Weight
    397.47
  • Scientific Description
    gamma-Secretase modulator 12 (Compound 1a) is a selective compound that effectively reduces amyloid-beta42 (Abeta42) levels with an IC50 of 0.39 microM, specifically designed for Alzheimers disease research. Notably, gamma-Secretase modulator 12 exhibits a favorable brain/plasma ratio (Kp, brain = 0.72) in mice [1].
  • Shelf life instruction
    3 years
  • SMILES
    CC1=C(N2C(C(OCC3=CC=CC=C3)=CC=C2)=N1)C=4C=C5C(=CC4)C(=O)N(CC)C5
  • Storage Instruction
    -20°C
  • UNSPSC
    12352204