Ganglioside GM3 Mixture (sodium salt) [54827-14-4]
T35588
Overview
- SupplierTargetMol Chemicals
- Product NameGanglioside GM3 Mixture (sodium salt) [54827-14-4]
- Delivery Days Customer16
- CAS Number54827-14-4
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameGanglioside GM3 Mixture (sodium salt)
- Molecular FormulaC59H107N2NaO21
- Molecular Weight1203.488
- Scientific DescriptionGanglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation. It suppresses angiogenesis and reduces proliferation and migration of human umbilical vein endothelial cells (HUVECs) when used at a concentration of 20 microM via inhibition of VEGFR2 and Akt phosphorylation. Ganglioside GM3 induces dissociation of the insulin receptor-caveolin-1 complex from lipid microdomains, functioning as an inhibitor of insulin signaling and contributing to insulin resistance in adipocytes. Ganglioside GM3 mixture contains ganglioside GM3 molecular species with C18:1 and C20:1 fatty acyl chains.
- Shelf life instruction3 years
- SMILES[Na+].CCCCCCCCCCCCCCCCCC(=O)NC(COC1OC(CO)C(OC2OC(CO)C(O)C(OC3(CC(O)C(NC(C)=O)C(O3)C(O)C(O)CO)C([O-])=O)C2O)C(O)C1O)C(O)\C=C\CCCCCCCCCCCCC
- Storage Instruction-20°C
- UNSPSC12352200
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