Bio-Connect
Ganglioside GM3 Mixture (sodium salt) [54827-14-4]

Ganglioside GM3 Mixture (sodium salt) [54827-14-4]

T35588
TargetMol Chemicals
CAS Number54827-14-4
Product group Chemicals
Molecular Weight1203.488
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Ganglioside GM3 Mixture (sodium salt) [54827-14-4]
  • Delivery Days Customer
    16
  • CAS Number
    54827-14-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Ganglioside GM3 Mixture (sodium salt)
  • Molecular Formula
    C59H107N2NaO21
  • Molecular Weight
    1203.488
  • Scientific Description
    Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation. It suppresses angiogenesis and reduces proliferation and migration of human umbilical vein endothelial cells (HUVECs) when used at a concentration of 20 microM via inhibition of VEGFR2 and Akt phosphorylation. Ganglioside GM3 induces dissociation of the insulin receptor-caveolin-1 complex from lipid microdomains, functioning as an inhibitor of insulin signaling and contributing to insulin resistance in adipocytes. Ganglioside GM3 mixture contains ganglioside GM3 molecular species with C18:1 and C20:1 fatty acyl chains.
  • Shelf life instruction
    3 years
  • SMILES
    [Na+].CCCCCCCCCCCCCCCCCC(=O)NC(COC1OC(CO)C(OC2OC(CO)C(O)C(OC3(CC(O)C(NC(C)=O)C(O3)C(O)C(O)CO)C([O-])=O)C2O)C(O)C1O)C(O)\C=C\CCCCCCCCCCCCC
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200