WB analysis of human tonsil lysate using GTX88689 GCH1 antibody, Internal. Dilution : 0.5microg/ml Loading : 35microg protein in RIPA buffer
WB analysis of human tonsil lysate using GTX88689 GCH1 antibody, Internal. Dilution : 0.5microg/ml Loading : 35microg protein in RIPA buffer
GCH1 antibody, Internal
GTX88689
Overview
- SupplierGeneTex
- Product NameGCH1 antibody, Internal
- Delivery Days Customer9
- Antibody SpecificityThis antibody is expected to recognize all four isoforms (NP_000152.1 ; NP_001019195.1 ; NP_001019241.1 ; NP_001019242.1)
- Application Supplier NoteWB: 0.5-1.5microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID2643
- Target nameGCH1
- Target descriptionGTP cyclohydrolase 1
- Target synonymsdystonia 14; DYT14; DYT5; DYT5a; GCH; GTP cyclohydrolase 1; GTP cyclohydrolase I; GTPCH1; GTP-CH-1; GTP-CH-I; guanosine 5'-triphosphate cyclohydrolase I; HPABH4B
- HostGoat
- IsotypeIgG
- Protein IDP30793
- Protein NameGTP cyclohydrolase 1
- Scientific DescriptionThis gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203